The Knoxville Blue Bullets play Illinois high school football (IHSA) as a 2010 member of the Prairieland Blue conference. Knoxville High School is located in Knoxville, Illinois. Knoxville is in Knox county. The Blue Bullets' Illinois Pigskin region is the 309 Football Region. They are coached by Toby Vallas entering his 8th year of coaching at Knoxville. The school Athletic Director is Chad Bahnks.

The schools 2010 enrollment numbers are 335. The Blue Bullets' colors are Navy Blue/Old Gold. Knoxville has qualified for the IHSA playoffs 11 times, the last playoff appearance was 2009. They have qualified for the playoffs 1 consecutive years.